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Comparative Study
. 2017 Sep;131(5):1203-1210.
doi: 10.1007/s00414-017-1564-z. Epub 2017 Feb 27.

How many single nucleotide polymorphisms (SNPs) are needed to replace short tandem repeats (STRs) in forensic applications?

Hyo-Jung Lee  1 , Jae Won Lee  2 , Su Jin Jeong  2 , Mira Park  3
Affiliations
Comparative Study

How many single nucleotide polymorphisms (SNPs) are needed to replace short tandem repeats (STRs) in forensic applications?

Hyo-Jung Lee et al. Int J Legal Med. 2017 Sep.

Abstract

Short tandem repeats (STRs) are the most commonly used forms of genetic information in forensic identification. In recent times, advances in the information on single nucleotide polymorphisms (SNPs) have raised the possibility that these markers could replace the forensically established STRs. In this work, we conducted comparative simulation studies that allowed us to estimate the number of SNPs needed if these markers were used instead of STRs in criminal cases and paternity investigations.

Keywords: Short tandem repeats; Single nucleotide polymorphisms.

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