doi: 10.1007/s10517-017-3652-y.
Epub 2017 Feb 27.
Systemic Amyloidosis Model on Young Mice
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- PMID: 28243908
- DOI: 10.1007/s10517-017-3652-y
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Systemic Amyloidosis Model on Young Mice
Bull Exp Biol Med.
2017 Feb.
Abstract
Subcutaneous daily injection (with neglect of aseptics) of 0.5 ml solution of soybean cream substitute (10% volume in distilled water) during 30 days caused systemic amyloidosis in 30-day-old mice. All the known methods for induction of systemic amyloidosis are based on the use of old animals, as senile tissue bradytrophy allows effective simulation of amyloidosis.
Keywords: amyloidosis model; young mice.
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