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. 2017 Feb;162(4):520-523.
doi: 10.1007/s10517-017-3652-y. Epub 2017 Feb 27.

Systemic Amyloidosis Model on Young Mice

V A Kozlov  1 , S P Sapozhnikov  2 , P B Karyshev  3 , A I Sheptukhina  2 , O V Nikolaeva  2
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Systemic Amyloidosis Model on Young Mice

V A Kozlov et al. Bull Exp Biol Med. 2017 Feb.

Abstract

Subcutaneous daily injection (with neglect of aseptics) of 0.5 ml solution of soybean cream substitute (10% volume in distilled water) during 30 days caused systemic amyloidosis in 30-day-old mice. All the known methods for induction of systemic amyloidosis are based on the use of old animals, as senile tissue bradytrophy allows effective simulation of amyloidosis.

Keywords: amyloidosis model; young mice.

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