Genetic screening enters the single-cell era
- PMID: 28245215
- DOI: 10.1038/nmeth.4196
Genetic screening enters the single-cell era
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Perturb-Seq: Dissecting Molecular Circuits with Scalable Single-Cell RNA Profiling of Pooled Genetic Screens.Cell. 2016 Dec 15;167(7):1853-1866.e17. doi: 10.1016/j.cell.2016.11.038. Cell. 2016. PMID: 27984732 Free PMC article.
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A Multiplexed Single-Cell CRISPR Screening Platform Enables Systematic Dissection of the Unfolded Protein Response.Cell. 2016 Dec 15;167(7):1867-1882.e21. doi: 10.1016/j.cell.2016.11.048. Cell. 2016. PMID: 27984733 Free PMC article.
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Dissecting Immune Circuits by Linking CRISPR-Pooled Screens with Single-Cell RNA-Seq.Cell. 2016 Dec 15;167(7):1883-1896.e15. doi: 10.1016/j.cell.2016.11.039. Cell. 2016. PMID: 27984734
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Pooled CRISPR screening with single-cell transcriptome readout.Nat Methods. 2017 Mar;14(3):297-301. doi: 10.1038/nmeth.4177. Epub 2017 Jan 18. Nat Methods. 2017. PMID: 28099430 Free PMC article.
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