The Sweetness of Embryonic Elongation and Differentiation
- PMID: 28245916
- DOI: 10.1016/j.devcel.2017.02.012
The Sweetness of Embryonic Elongation and Differentiation
Abstract
Metabolic pathways play a vital yet poorly understood role in embryogenesis. In this issue of Developmental Cell, Bulusu et al. (2017) and Oginuma et al. (2017) provide insights into the intricate relationship between metabolism and morphogenesis, showing that glycolysis facilitates body elongation and balances neural and mesodermal differentiation.
Copyright © 2017 Elsevier Inc. All rights reserved.
Comment on
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Spatiotemporal Analysis of a Glycolytic Activity Gradient Linked to Mouse Embryo Mesoderm Development.Dev Cell. 2017 Feb 27;40(4):331-341.e4. doi: 10.1016/j.devcel.2017.01.015. Dev Cell. 2017. PMID: 28245920 Free PMC article.
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A Gradient of Glycolytic Activity Coordinates FGF and Wnt Signaling during Elongation of the Body Axis in Amniote Embryos.Dev Cell. 2017 Feb 27;40(4):342-353.e10. doi: 10.1016/j.devcel.2017.02.001. Dev Cell. 2017. PMID: 28245921 Free PMC article.
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