Mitochondrial Calcium Sparkles Light Up Astrocytes
- PMID: 28245918
- DOI: 10.1016/j.devcel.2017.02.013
Mitochondrial Calcium Sparkles Light Up Astrocytes
Abstract
Discrete calcium signals in the fine processes of astrocytes are a recent discovery and a new mystery. In a recent issue of Neuron, Agarwal et al. (2017) report that calcium efflux from mitochondria during brief openings of the mitochondrial permeability transition pore (mPTP) contribute to calcium microdomains.
Crown Copyright © 2017. Published by Elsevier Inc. All rights reserved.
Comment on
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Transient Opening of the Mitochondrial Permeability Transition Pore Induces Microdomain Calcium Transients in Astrocyte Processes.Neuron. 2017 Feb 8;93(3):587-605.e7. doi: 10.1016/j.neuron.2016.12.034. Epub 2017 Jan 26. Neuron. 2017. PMID: 28132831 Free PMC article.
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