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. 1987 Nov:68 ( Pt 11):2933-8.
doi: 10.1099/0022-1317-68-11-2933.

Identification of human papillomavirus type 16 E7 protein by monoclonal antibodies

T Oltersdorf  1 , K Seedorf, W Röwekamp, L Gissmann
Affiliations

Identification of human papillomavirus type 16 E7 protein by monoclonal antibodies

T Oltersdorf et al. J Gen Virol. 1987 Nov.

Abstract

A number of human papillomavirus (HPV) type 16 proteins have recently been identified in human cervical carcinoma cell lines using polyclonal antisera against papillomavirus gene products expressed in Escherichia coli. E7 protein has been found to be the most abundant papillomavirus protein in these cells. Here we describe a panel of monoclonal antibodies recognizing a 15K Mr non-glycosylated cytoplasmic HPV-16 E7 protein. One of the antibodies cross-reacted with HPV-18 E7 protein.

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