A Retrospective Video Analysis of Canonical Babbling and Volubility in Infants with Fragile X Syndrome at 9-12 Months of Age

doi:10.1007/s10803-017-3033-4

. 2017 Apr;47(4):1193-1206.

doi: 10.1007/s10803-017-3033-4.

A Retrospective Video Analysis of Canonical Babbling and Volubility in Infants with Fragile X Syndrome at 9-12 Months of Age

Katie Belardi¹, Linda R Watson², Richard A Faldowski³, Heather Hazlett⁴, Elizabeth Crais², Grace T Baranek³, Cara McComish², Elena Patten⁵, D Kimbrough Oller^{6

7}

Affiliations

¹ The Department of Speech-Language Pathology, Duquesne University, 409 Fisher Hall, 701 Forbes Avenue, Pittsburgh, PA, 15282, USA. belardik@duq.edu.
² The Department of Allied Health Sciences, The University of North Carolina - Chapel Hill, Bondurant Hall, CB #7190, Chapel Hill, NC, 27599-7190, USA.
³ The Department of Allied Health Sciences and The Office of Research, The University of North Carolina - Chapel Hill, Bondurant Hall, CB #7122, Chapel Hill, NC, 27599-7122, USA.
⁴ The Carolina Institute for Developmental Disabilities, The University of North Carolina - Chapel Hill, CB #7255, Chapel Hill, NC, 27599-7255, USA.
⁵ Department of Audiology and Speech Pathology, University of Tennessee Health Science Center, 434 South Stadium Hall, Knoxville, TN, 37996, USA.
⁶ The University of Memphis, 807 Jefferson Avenue, Memphis, TN, 28105, USA.
⁷ Konrad Lorenz Institute for Evolution and Cognition Research, Klosterneuburg, Austria.

PMID: 28247019
PMCID: PMC5450668
DOI: 10.1007/s10803-017-3033-4

A Retrospective Video Analysis of Canonical Babbling and Volubility in Infants with Fragile X Syndrome at 9-12 Months of Age

Katie Belardi et al. J Autism Dev Disord. 2017 Apr.

. 2017 Apr;47(4):1193-1206.

doi: 10.1007/s10803-017-3033-4.

Authors

Katie Belardi¹, Linda R Watson², Richard A Faldowski³, Heather Hazlett⁴, Elizabeth Crais², Grace T Baranek³, Cara McComish², Elena Patten⁵, D Kimbrough Oller^{6

7}

Affiliations

¹ The Department of Speech-Language Pathology, Duquesne University, 409 Fisher Hall, 701 Forbes Avenue, Pittsburgh, PA, 15282, USA. belardik@duq.edu.
² The Department of Allied Health Sciences, The University of North Carolina - Chapel Hill, Bondurant Hall, CB #7190, Chapel Hill, NC, 27599-7190, USA.
³ The Department of Allied Health Sciences and The Office of Research, The University of North Carolina - Chapel Hill, Bondurant Hall, CB #7122, Chapel Hill, NC, 27599-7122, USA.
⁴ The Carolina Institute for Developmental Disabilities, The University of North Carolina - Chapel Hill, CB #7255, Chapel Hill, NC, 27599-7255, USA.
⁵ Department of Audiology and Speech Pathology, University of Tennessee Health Science Center, 434 South Stadium Hall, Knoxville, TN, 37996, USA.
⁶ The University of Memphis, 807 Jefferson Avenue, Memphis, TN, 28105, USA.
⁷ Konrad Lorenz Institute for Evolution and Cognition Research, Klosterneuburg, Austria.

PMID: 28247019
PMCID: PMC5450668
DOI: 10.1007/s10803-017-3033-4

Abstract

An infant's vocal capacity develops significantly during the first year of life. Research suggests early measures of pre-speech development, such as canonical babbling and volubility, can differentiate typical versus disordered development. This study offers a new contribution by comparing early vocal development in 10 infants with Fragile X syndrome and 14 with typical development. Results suggest infants with Fragile X syndrome produce fewer syllables and have significantly lower canonical babbling ratios compared to infants who are typically developing. Furthermore, the particular measures of babbling were strong predictors of group membership, adding evidence regarding the possible utility of these markers in early identification.

Keywords: Canonical babbling; Fragile X syndrome; Language development.

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Figures

**Figure 1a**
Group canonical babbling ratios by participant across 10-minute sample. Error bars represent standard error.

**Figure 1b**
Group volubility across 10-minute samples. Error bars represent standard errors.

See this image and copyright information in PMC

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References

1. Abbeduto L, Hagerman RJ. Language and communication in fragile X syndrome. Mental Retardation and Developmental Disabilities Research Reviews. 1997;3(4):313–322.
1. Abbeduto L, Murphy MM, Cawthon SW, Richmond EK, Weissman MD, Karadottir S, O’Brien A. Receptive language skills of adolescents and young adults with Down or fragile X syndrome. American Journal on Mental Retardation. 2003;108(3):149–160. - PubMed
1. Bailey DB, Jr, Hatton DD, Skinner M. Early developmental trajectories of males with fragile X syndrome. American Journal on Mental Retardation. 1998;103(1):29–39. - PubMed
1. Bailey DB, Raspa M, Bishop E, Holiday D. No change in the age of diagnosis for fragile X syndrome: Findings from a national parent survey. Pediatrics. 2009;124(2):527–533. - PubMed
1. Baranek GT. Autism during infancy: A retrospective video analysis of sensory-motor and social behaviors at 9–12 months of age. Journal of Autism and Developmental Disorders. 1999;29(3):213–224. - PubMed

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[1] Abbeduto L, Hagerman RJ. Language and communication in fragile X syndrome. Mental Retardation and Developmental Disabilities Research Reviews. 1997;3(4):313–322.

[2] Abbeduto L, Hagerman RJ. Language and communication in fragile X syndrome. Mental Retardation and Developmental Disabilities Research Reviews. 1997;3(4):313–322.

[3] Abbeduto L, Murphy MM, Cawthon SW, Richmond EK, Weissman MD, Karadottir S, O’Brien A. Receptive language skills of adolescents and young adults with Down or fragile X syndrome. American Journal on Mental Retardation. 2003;108(3):149–160. - PubMed

[4] Abbeduto L, Murphy MM, Cawthon SW, Richmond EK, Weissman MD, Karadottir S, O’Brien A. Receptive language skills of adolescents and young adults with Down or fragile X syndrome. American Journal on Mental Retardation. 2003;108(3):149–160. - PubMed

[5] Bailey DB, Jr, Hatton DD, Skinner M. Early developmental trajectories of males with fragile X syndrome. American Journal on Mental Retardation. 1998;103(1):29–39. - PubMed

[6] Bailey DB, Jr, Hatton DD, Skinner M. Early developmental trajectories of males with fragile X syndrome. American Journal on Mental Retardation. 1998;103(1):29–39. - PubMed

[7] Bailey DB, Raspa M, Bishop E, Holiday D. No change in the age of diagnosis for fragile X syndrome: Findings from a national parent survey. Pediatrics. 2009;124(2):527–533. - PubMed

[8] Bailey DB, Raspa M, Bishop E, Holiday D. No change in the age of diagnosis for fragile X syndrome: Findings from a national parent survey. Pediatrics. 2009;124(2):527–533. - PubMed

[9] Baranek GT. Autism during infancy: A retrospective video analysis of sensory-motor and social behaviors at 9–12 months of age. Journal of Autism and Developmental Disorders. 1999;29(3):213–224. - PubMed

[10] Baranek GT. Autism during infancy: A retrospective video analysis of sensory-motor and social behaviors at 9–12 months of age. Journal of Autism and Developmental Disorders. 1999;29(3):213–224. - PubMed

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A Retrospective Video Analysis of Canonical Babbling and Volubility in Infants with Fragile X Syndrome at 9-12 Months of Age

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A Retrospective Video Analysis of Canonical Babbling and Volubility in Infants with Fragile X Syndrome at 9-12 Months of Age

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