Twist of fate for skeletal muscle mesenchymal cells
- PMID: 28248307
- DOI: 10.1038/ncb3482
Twist of fate for skeletal muscle mesenchymal cells
Abstract
Skeletal muscles are composed of different types of fibres. Can these be thought of as distinct lineages with specific lineage-restricted progenitors? A provocative study now proposes that mesenchymal cells expressing the transcription factor Twist2 act as myogenic progenitors with selective type IIb fibre-differentiation potential.
Comment on
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A Twist2-dependent progenitor cell contributes to adult skeletal muscle.Nat Cell Biol. 2017 Mar;19(3):202-213. doi: 10.1038/ncb3477. Epub 2017 Feb 20. Nat Cell Biol. 2017. PMID: 28218909 Free PMC article.
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