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. 2017 Apr;18(4):212-213.

doi: 10.1038/nrm.2017.18. Epub 2017 Mar 1.

Non-coding RNA: The cancer link(RNA) between PIP₃ and AKT

Eytan Zlotorynski

PMID: 28248320
DOI: 10.1038/nrm.2017.18

Comment

Non-coding RNA: The cancer link(RNA) between PIP₃ and AKT

Eytan Zlotorynski. Nat Rev Mol Cell Biol. 2017 Apr.

. 2017 Apr;18(4):212-213.

doi: 10.1038/nrm.2017.18. Epub 2017 Mar 1.

Author

Eytan Zlotorynski

PMID: 28248320
DOI: 10.1038/nrm.2017.18

No abstract available

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The LINK-A lncRNA interacts with PtdIns(3,4,5)P₃ to hyperactivate AKT and confer resistance to AKT inhibitors.
Lin A, Hu Q, Li C, Xing Z, Ma G, Wang C, Li J, Ye Y, Yao J, Liang K, Wang S, Park PK, Marks JR, Zhou Y, Zhou J, Hung MC, Liang H, Hu Z, Shen H, Hawke DH, Han L, Zhou Y, Lin C, Yang L. Lin A, et al. Nat Cell Biol. 2017 Mar;19(3):238-251. doi: 10.1038/ncb3473. Epub 2017 Feb 20. Nat Cell Biol. 2017. PMID: 28218907 Free PMC article.

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