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Meta-Analysis
. 2017 Mar;96(9):e6064.
doi: 10.1097/MD.0000000000006064.

Acupuncture therapy in the management of the clinical outcomes for temporomandibular disorders: A PRISMA-compliant meta-analysis

Jun-Yi Wu  1 , Chao Zhang, Yang-Peng Xu, Ya-Yu Yu, Le Peng, Wei-Dong Leng, Yu-Ming Niu, Mo-Hong Deng
Affiliations
Meta-Analysis

Acupuncture therapy in the management of the clinical outcomes for temporomandibular disorders: A PRISMA-compliant meta-analysis

Jun-Yi Wu et al. Medicine (Baltimore). 2017 Mar.

Abstract

Purpose: The purpose of this study was to evaluate conventional acupuncture therapy in the management of clinical outcomes for temporomandibular disorders (TMD) in adults.

Methods: The electronic databases PubMed, EMBASE, Cochrane Central Register of Controlled Trials, and Clinical Trails.gov were searched for reports published until March 31, 2016.

Results: Nine eligible studies from 8 publications involving 231 patients were included in the meta-analysis. A comparison of the main outcome of visual analog scale (VAS) values of pain between the acupuncture group and control group showed a significant decrease (MD = -0.98, 95% CI [-1.62, -0.34], I=54%, P = 0.003) in the VAS following acupuncture treatment. However, subgroup analysis according to the type of sham control group indicated that there were significant differences in the results when sham acupuncture was used as the control group (MD = -1.54, 95% CI [-2.63, -0.45], I=58%, P = 0.006) as well as when sham laser treatment was used as the control group (MD = -1.29, 95% CI [-2.32, -0.27], I = 0%, P = 0.01). However, there was no significant difference when the splint treatment group was used as the control group (MD = -0.09, 95% CI [-0.69, 0.50], I = 0%, P = 0.76). Subgroup analyses of VAS for pain by the classification of diseases indicated that the myogenous TMD subgroup demonstrated a significant difference (MD = -1.49, 95% CI [-2.45, -0.53], I = 47%, P = 0.002), and TMD showed no statistically significant difference (MD = -0.42, 95% CI [-1.14, 0.30], I = 46%, P = 0.25). Subgroup analysis according to whether the subgroup penetrated the skin showed that nonpenetrating sham acupuncture as the control group showed a significant difference (MD = -1.56, 95% CI [-2.70, -0.41], I = 58%, P = 0.008) compared with the conventional acupuncture as the treatment modality, while penetrating sham acupuncture as the control group showed no significant difference (MD = -1.29, 95% CI [-3.40, 0.82], I = not applicable, P = 0.23). No publication bias was observed considering the symmetry of the funnel plots.

Conclusions: Our results indicate that conventional acupuncture therapy is effective in reducing the degree of pain in patients with TMD, especially those with myofascial pain symptoms.

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Conflict of interest statement

The authors have no conflicts of interest to disclose.

Figures

Figure 1
Figure 1
Summary of trial identification and selection.
Figure 2
Figure 2
Forest plot of subgroup analysis of VAS for pain according to the type of sham control group. VAS = visual analog scale.
Figure 3
Figure 3
Forest plot of subgroup analysis of VAS for pain according to the classification of diseases. VAS = visual analog scale.
Figure 4
Figure 4
Forest plot of subgroup analysis of VAS for pain according to whether to penetrate the skin in control group. VAS = visual analog scale.
Figure 5
Figure 5
Forest plot of subgroup analysis of the change in MMO according to the classification of diseases. MMO = maximum mouth opening.
Figure 6
Figure 6
Forest plot of the VAS of muscle tenderness. VAS = visual analog scale.
Figure 7
Figure 7
Forest plot of the VAS of functional impairment. VAS = visual analog scale.
Figure 8
Figure 8
Funnel plot of subgroup analysis of the VAS of pain according to the classification of diseases. VAS = visual analog scale.
See this image and copyright information in PMC

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