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. 1987 Dec;330(6148):537-43.
doi: 10.1038/330537a0.

Growth hormone receptor and serum binding protein: purification, cloning and expression

D W Leung  1 , S A Spencer, G Cachianes, R G Hammonds, C Collins, W J Henzel, R Barnard, M J Waters, W I Wood
Affiliations

Growth hormone receptor and serum binding protein: purification, cloning and expression

D W Leung et al. Nature. 1987 Dec.

Abstract

A putative growth hormone receptor from rabbit liver and the growth hormone binding protein from rabbit serum have the same amino-terminal amino-acid sequence, indicating that the binding protein corresponds to the extracellular hormone-binding domain of the liver receptor. The complete amino-acid sequences derived from complementary DNA clones encoding the putative human and rabbit growth hormone receptors are not similar to other known proteins, demonstrating a new class of transmembrane receptors.

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