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Observational Study
. 2017 Jan;34(1):21-27.
doi: 10.4274/balkanmedj.2015.1125. Epub 2017 Jan 5.

The Role of Follow-up in Monitoring the Outcomes of Prematurity in a Cohort of Romanian Infants

Anca Bivoleanu  1 , Andreea Avasiloaiei  2 , Mihaela Moscalu  3 , Maria Stamatin  2
Affiliations
Observational Study

The Role of Follow-up in Monitoring the Outcomes of Prematurity in a Cohort of Romanian Infants

Anca Bivoleanu et al. Balkan Med J. 2017 Jan.

Abstract

Background: The rate of preterm births in Romania is one of the highest among European countries. However, there is little information regarding the ways in which premature birth affects the outcome in Romanian preterm infants.

Aims: To investigate the effects of early developmental intervention after discharge from the hospital on motor and cognitive development in preterm infants.

Study design: Longitudinal observational study.

Methods: We performed the Amiel-Tison neurologic evaluation at discharge and the Bayley Scales of Infant Development from 3 to 24 months. Based on these evaluations, an outcome score was formulated.

Results: Between 2007 and 2010, 1157 of 2793 premature infants were included into the study. There was a negative correlation between the number of evaluations and the risk of developing neurologic sequelae (p<0.001). The correlation analysis demonstrated a significant association between the final category of risk at the end of the follow up program and the degree of compliance (p<0.01). At 24 months evaluation, there was a correlation between the low gestational age and the risk of developing severe neurologic sequelae (p<0.001).

Conclusion: This study shows the importance of follow up program in decreasing the risk of developing neurologic sequelae in preterm infants.

Keywords: Neurologic sequelae; infants; monitoring; prematurity.

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Conflict of interest statement

Conflict of Interest: No conflict of interest was declared by the authors.

Figures

Figure 1
Figure 1. The incidence of prematurity among study subjects.GA: gestational age
Figure 2
Figure 2. Correlation between the degree of risk and number of evaluations.
Figure 3
Figure 3. Distribution of preterm infants according to the degree of risk and gestational age. GA: gestational age
Figure 4
Figure 4. Amiel-Tison examination and BSID II examination versus number of evaluations and degree of risk.L: low; M: moderate; S: severe
See this image and copyright information in PMC

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References

    1. Costeloe KL, Hennessy EM, Haider S, Stacey F, Marlow N, Draper ES. Short term outcomes after extreme preterm birth in England: comparison of two birth cohorts in 1995 and 2006 (the EPICure studies) BMJ. 2012;345:e7976. - PMC - PubMed
    1. Boyle EM, Poulsen G, Field DJ, Kurinczuk JJ, Wolke D, Alfirevic Z, et al. Effects of gestational age at birth on health outcomes at 3 and 5 years of age: population based cohort study. BMJ. 2012;344:e896. - PMC - PubMed
    1. Kerstjens JM, Bocca-Tjeertes IF, Winter AF, de, Reijneveld SA, Bos AF. Neonatal morbidities and developmental delay in moderately preterm-born children. Pediatrics. 2012;130:e265–72. - PubMed
    1. Stoll BJ, Hansen NI, Bell EF, Shankaran S, Laptook AR, Walsh MC, et al Eunice Kennedy Shriver National Institute of Child Health and Human Development Neonatal Research Network. Neonatal outcomes of extremely preterm infants from the NICHD Neonatal Research Network. Pediatrics. 2010;126:443–56. - PMC - PubMed
    1. Platt MJ, Cans C, Johnson A, Surman G, Topp M, Torrioli MG, et al. Trends in cerebral palsy among infants of very low birth weight (<1500 grams) or born prematurely (<32 wk) in 16 European centres. Lancet. 2007;369:43–50. - PubMed

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