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Comparative Study
. 1987 Nov 25;15(22):9215-25.
doi: 10.1093/nar/15.22.9215.

Unusual features of CpG-rich (HTF) islands in the human alpha globin complex: association with non-functional pseudogenes and presence within the 3' portion of the zeta gene

N Fischel-Ghodsian  1 , R D Nicholls, D R Higgs
Affiliations
Free PMC article
Comparative Study

Unusual features of CpG-rich (HTF) islands in the human alpha globin complex: association with non-functional pseudogenes and presence within the 3' portion of the zeta gene

N Fischel-Ghodsian et al. Nucleic Acids Res. .
Free PMC article

Abstract

We have characterised a cluster of CpG rich (HTF) islands in the alpha-globin complex and report here two unusual features: The human embryonic zeta 2-globin gene is associated with an HTF island within its 3' portion rather than at the 5' end. Furthermore at least two non-functional pseudogenes within the cluster (psi zeta 1 and psi alpha 2) are associated with CpG rich islands.

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References

    1. Cell. 1980 May;20(1):119-30 - PubMed
    1. Nucleic Acids Res. 1987 Aug 11;15(15):6197-207 - PubMed
    1. Cell. 1981 Dec;27(2 Pt 1):279-88 - PubMed
    1. Cell. 1982 Dec;31(3 Pt 2):553-63 - PubMed
    1. Anal Biochem. 1984 Feb;137(1):266-7 - PubMed

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