Current evidence supports use of lipid rescue therapy in local anaesthetic systemic toxicity

Affiliations

Editorial

G Weinberg. Acta Anaesthesiol Scand. 2017 Apr.

. 2017 Apr;61(4):365-368.

doi: 10.1111/aas.12870.

¹ Department of Anesthesiology M/C 515, University of Illinois Hospital, Jesse Brown VA Medical Center, Chicago, IL, USA.

No abstract available

Comment on

Phosphorylation of GSK-3β mediates intralipid-induced cardioprotection against ischemia/reperfusion injury.
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Effect of Intralipid® on the Dose of Ropivacaine or Levobupivacaine Tolerated by Volunteers: A Clinical and Pharmacokinetic Study.
Dureau P, Charbit B, Nicolas N, Benhamou D, Mazoit JX. Dureau P, et al. Anesthesiology. 2016 Sep;125(3):474-83. doi: 10.1097/ALN.0000000000001230. Anesthesiology. 2016. PMID: 27404223 Clinical Trial.
Current evidence is not in support of lipid rescue therapy in local anaesthetic systemic toxicity.
Rosenberg PH. Rosenberg PH. Acta Anaesthesiol Scand. 2016 Sep;60(8):1029-32. doi: 10.1111/aas.12743. Acta Anaesthesiol Scand. 2016. PMID: 27465522 No abstract available.