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. 2017 Mar 2;20(3):296-297.
doi: 10.1016/j.stem.2017.02.005.

Pericytes or Mesenchymal Stem Cells: Is That the Question?

Elena Cano  1 , Véronique Gebala  1 , Holger Gerhardt  2
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Pericytes or Mesenchymal Stem Cells: Is That the Question?

Elena Cano et al. Cell Stem Cell. .
Free article

Abstract

For almost a decade, mesenchymal stem cells (MSCs) were believed to reside as perivascular cells in vivo. In this issue of Cell Stem Cell, Guimarães-Camboa et al. (2017) challenge this idea and use lineage tracing to demonstrate that perivascular cells do not behave as tissue-specific progenitors in various organs, despite showing MSC potential in vitro.

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  • Pericytes of Multiple Organs Do Not Behave as Mesenchymal Stem Cells In Vivo.
    Guimarães-Camboa N, Cattaneo P, Sun Y, Moore-Morris T, Gu Y, Dalton ND, Rockenstein E, Masliah E, Peterson KL, Stallcup WB, Chen J, Evans SM. Guimarães-Camboa N, et al. Cell Stem Cell. 2017 Mar 2;20(3):345-359.e5. doi: 10.1016/j.stem.2016.12.006. Epub 2017 Jan 19. Cell Stem Cell. 2017. PMID: 28111199 Free PMC article.

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