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Editorial
. 2017 Apr;139(4):1131-1134.
doi: 10.1016/j.jaci.2017.02.008. Epub 2017 Feb 28.

The National Biome Initiative: An allergy perspective

Affiliations
Editorial

The National Biome Initiative: An allergy perspective

Glenn T Furuta et al. J Allergy Clin Immunol. 2017 Apr.
No abstract available

Keywords: Eosinophilic esophagitis; allergy; asthma; biome initiative; microbiome.

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Conflict of interest statement

Disclosure of potential conflict of interest: G. T. Furuta has consultant arrangements with Shire, has received a grant from the National Institutes of Health, and has received royalties from UpToDate. S. S. Aceves has received a grant and travel support from the National Institutes of Health/National Institute of Allergy and Infectious Diseases, is a member of the Medical Advisory Board for the American Partnership for Eosinophilic Disorders, has a patent for oral viscous budesonide.

Figures

FIG 1.
FIG 1.
The microbiota of allergic diseases. Environmental exposures alter bacterial diversity and increase inflammation. The result is tissue and gut dysbiosis with decreased bacterial diversity and changes in the microbiome of target organs. The alterations in normal flora likely interact with increased inflammation to alter patient phenotypes, such as disease response.

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