Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2017 Mar 1;13(2):441-447.
doi: 10.5114/aoms.2016.60387. Epub 2016 Jun 6.

The impact of the Polish mass breast cancer screening program on prognosis in the Pomeranian Province

Piotr Woźniacki  1 , Jarosław Skokowski  1 , Krzystof Bartoszek  2 , Anna Kosowska  1 , Leszek Kalinowski  3 , Janusz Jaśkiewicz  1
Affiliations

The impact of the Polish mass breast cancer screening program on prognosis in the Pomeranian Province

Piotr Woźniacki et al. Arch Med Sci. .

Abstract

Introduction: Mammographic screening results in diagnosis of less advanced breast cancer (BC). A meta-analysis of randomized clinical trials confirmed that BC screening reduces mortality. In 2007, the National Breast Cancer Screening Program (NBCSP) was established in Poland with the crucial aim of reducing mortality from BC. The purpose of this study was to assess the impact of participation in the NBCSP on prognosis.

Material and methods: A single institution, non-randomized retrospective study was undertaken. The study population comprised 643 patients with BC treated in the Department of Surgical Oncology (DSO) at the Medical University of Gdansk over a 4-year period, from 01.01.2007 until 31.12.2010. Patients were divided into two groups: group A - patients who participated in the NBCSP (n = 238, 37.0%); and group B - patients who did not participate in the NBCSP (n = 405, 63.0%).

Results: Statistical analysis revealed that group A displayed a less advanced AJCC stage (more patients in AJCC stage I, p = 0.002), lower tumor diameter (more patients with pT1, p = 0.006, and pT < 15 mm, p = 0.008) and a lower incidence of metastases to axillary lymph nodes (more patients with pNO, p = 0.01). From 2009 to 2010 the NBCSP revealed a statistically significant benefit - significantly more patients in stage 0 + I (60.7% vs. 48.8%, p = 0.018) and with tumors pT < 15 mm (48.8% vs. 35.1%, p = 0.011) were observed in group A.

Conclusions: The study results revealed the beneficial impact of the NBCSP. Superior prognostic factors and favorable staging were observed in women who participated in the NBCSP.

Keywords: AJCC staging; breast cancer; mass screening; prognosis; prognostic factors; screening.

PubMed Disclaimer

Conflict of interest statement

The authors declare no conflict of interest.

Figures

Figure 1
Figure 1
Participation in the NBCP in Pomeranian Region (years 2007–2010)
Figure 2
Figure 2
The number of presentations of patients with BC treated in the DSO between 2007 and 2010
See this image and copyright information in PMC

References

    1. Ferlay J, Shin HR, Bray F, et al. Estimates of worldwide burden of cancer in 2008: GLOBOCAN 2008. Int J Cancer. 2010;127:2893–917. - PubMed
    1. Bevers TB, Anderson BO, Bonaccio E, et al. National Comprehensive Cancer Network. NCCN clinical practice guidelines in oncology: breast cancer screening and diagnosis. J Natl Compr Canc Netw. 2009;7:1060–96. - PubMed
    1. Gøtzsche PC, Nielsen M. Screening for breast cancer with mammography. Cochrane Database Syst Rev. 2011;19 CD001877. - PubMed
    1. Sant M, Allemani C, Santaquilani M, et al. EUROCARE Working Group. EUROCARE-4. Survival of cancer patients diagnosed in 1995-1999. Results and commentary. Eur J Cancer. 2009;45:931–91. - PubMed
    1. Sant M, Aareleid T, Berrino F, et al. EUROCARE Working Group. EUROCARE-3: survival of cancer patients diagnosed 1990-94. Results and commentary. Ann Oncol. 2003;14:61–118. - PubMed

LinkOut - more resources