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Review
. 2017:2017:9402849.
doi: 10.1155/2017/9402849. Epub 2017 Feb 5.

Therapeutic Role of Functional Components in Alliums for Preventive Chronic Disease in Human Being

Yawen Zeng  1 , Yuping Li  2 , Jiazhen Yang  3 , Xiaoying Pu  1 , Juan Du  1 , Xiaomeng Yang  1 , Tao Yang  1 , Shuming Yang  1
Affiliations
Review

Therapeutic Role of Functional Components in Alliums for Preventive Chronic Disease in Human Being

Yawen Zeng et al. Evid Based Complement Alternat Med. 2017.

Abstract

Objectives. Functional components in alliums have long been maintained to play a key role in modifying the major risk factors for chronic disease. To obtain a better understanding of alliums for chronic disease prevention, we conducted a systematic review for risk factors and prevention strategies for chronic disease of functional components in alliums, based on a comprehensive English literature search that was conducted using various electronic search databases, especially the PubMed, ISI Web of Science, and CNKI for the period 2007-2016. Allium genus especially garlic, onion, and Chinese chive is rich in organosulfur compounds, quercetin, flavonoids, saponins, and others, which have anticancer, preventive cardiovascular and heart diseases, anti-inflammation, antiobesity, antidiabetes, antioxidants, antimicrobial activity, neuroprotective and immunological effects, and so on. These results support Allium genus; garlic and onion especially may be the promising dietotherapeutic vegetables and organopolysulfides as well as quercetin mechanism in the treatment of chronic diseases. This review may be used as scientific basis for the development of functional food, nutraceuticals, and alternative drugs to improve the chronic diseases.

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Conflict of interest statement

The authors declare that there is no conflict of interests.

Figures

Figure 1
Figure 1
Possible mechanisms of functional components in allium for preventive chronic disease.
See this image and copyright information in PMC

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