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Case Reports
. 2017 Feb 28;5(3):e00222.
doi: 10.1002/rcr2.222. eCollection 2017 May.

Pneumonic-type mucinous lung adenocarcinoma diagnosed by transbronchial cryobiopsy

Affiliations
Case Reports

Pneumonic-type mucinous lung adenocarcinoma diagnosed by transbronchial cryobiopsy

Rick Balestra et al. Respirol Case Rep. .

Abstract

Primary lung adenocarcinoma with lepidic growth can mimic diffuse pulmonary parenchymal processes like infectious pneumonia or idiopathic inflammatory pneumonitis. We report a case of subacute pneumonitis refractory to antibiotic therapy and empirical corticosteroids, proven to be diffuse mucinous adenocarcinoma with lepidic growth on transbronchial cryobiopsy.

Keywords: Cryobiopsy; diffuse parenchymal lung disease; lung adenocarcinoma.

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Figures

Figure 1
Figure 1
Computed tomographic scans of the chest obtained at the onset of symptoms (A) and three months later (B). There are multifocal patchy ground glass pulmonary infiltrates that progress, evolving into large consolidated areas with air bronchograms.
Figure 2
Figure 2
Transbronchial lung cryobiopsy, haematoxylin, and eosin stain, showing irregular back‐to‐back glands with columnar lining epithelium and mucin, diagnostic of mucinous adenocarcinoma with lepidic growth. Also note the alveoli filled with mucin.

References

    1. Babiak A, Hetzel J, Krishna G, et al. 2009. Transbronchial cryobiopsy: a new tool for lung biopsies. Respiration 78(2):203–208. - PubMed
    1. Kropski JA, Pritchett JM, Mason WR, et al. 2013. Bronchoscopic cryobiopsy for the diagnosis of diffuse parenchymal lung disease. PLoS One 8(11):e78674. - PMC - PubMed
    1. Casoni GL, Tomassetti S, Cavazza A, et al. 2014. Transbronchial lung cryobiopsy in the diagnosis of fibrotic interstitial lung diseases. PLoS One 9(2):e86716. - PMC - PubMed
    1. Poletti V, Casoni GL, Gurioli C, et al. 2014. Lung cryobiopsies: a paradigm shift in diagnostic bronchoscopy? Respirology 19(5):645–654. - PubMed
    1. Ramaswamy A, Homer R, Killam J, et al. 2016. Comparison of transbronchial and cryobiopsies in evaluation of diffuse parenchymal lung disease. J. Bronchol. Interv. Pulmonol. 23(1):14–21. - PMC - PubMed

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