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Review
. 2017 Jul;31(3):145-150.
doi: 10.1016/j.trre.2017.02.003. Epub 2017 Feb 20.

Sex differences in transplantation

Jeremiah D Momper  1 , Michael L Misel  2 , Dianne B McKay  3
Affiliations
Review

Sex differences in transplantation

Jeremiah D Momper et al. Transplant Rev (Orlando). 2017 Jul.

Abstract

Sex plays a role in the incidence and progression of a wide variety of diseases and conditions related to transplantation. Additionally, a growing body of clinical and experimental evidence suggests that sex can impact the pharmacokinetics and pharmacodynamics of several commonly used immunosuppressive and anti-infective drugs in transplant recipients. A better understanding of these sex differences will facilitate advances in individualizing treatment for patients and improve outcomes of solid organ transplantation. Here, we provide a review of sex-related differences in transplantation and highlight opportunities for future research directions.

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