A second catalytic subunit of type-2A protein phosphatase from rabbit skeletal muscle
- PMID: 2826253
- DOI: 10.1016/0014-5793(87)80574-4
A second catalytic subunit of type-2A protein phosphatase from rabbit skeletal muscle
Abstract
A cDNA clone encoding a second type-2A protein phosphatase catalytic subunit (2A beta) was isolated from a rabbit skeletal muscle cDNA library constructed in lambda gt10. The deduced protein sequence (309 residues, 35.59 kDa) was 97% identical to that of phosphatase 2A alpha (309 residues, 35.58 kDa). At the nucleotide level, the two clones showed only 82% identity in the coding region. The results indicate the presence of at least two isoforms of protein phosphatase 2A in skeletal muscle.
Similar articles
-
Isolation and sequence analysis of a cDNA clone encoding a type-1 protein phosphatase catalytic subunit: homology with protein phosphatase 2A.FEBS Lett. 1987 Nov 2;223(2):340-6. doi: 10.1016/0014-5793(87)80316-2. FEBS Lett. 1987. PMID: 2822491
-
Isolation and sequence analysis of a cDNA clone encoding the entire catalytic subunit of a type-2A protein phosphatase.FEBS Lett. 1987 Sep 14;221(2):415-22. doi: 10.1016/0014-5793(87)80966-3. FEBS Lett. 1987. PMID: 3040474
-
Two isoforms of protein phosphatase 1 may be produced from the same gene.FEBS Lett. 1988 May 9;232(1):17-23. doi: 10.1016/0014-5793(88)80378-8. FEBS Lett. 1988. PMID: 2835264
-
Molecular cloning of cDNAs encoding two isoforms of the catalytic subunit of protein phosphatase 2A.Biochemistry. 1987 Nov 17;26(23):7215-20. doi: 10.1021/bi00397a003. Biochemistry. 1987. PMID: 2827745
-
Protein phosphatase 2A and the regulation of human papillomavirus gene activity.Curr Top Microbiol Immunol. 1994;186:121-9. doi: 10.1007/978-3-642-78487-3_7. Curr Top Microbiol Immunol. 1994. PMID: 8205837 Review. No abstract available.
Cited by
-
"Omics" of human sperm: profiling protein phosphatases.OMICS. 2013 Sep;17(9):460-72. doi: 10.1089/omi.2012.0119. Epub 2013 Jul 29. OMICS. 2013. PMID: 23895272 Free PMC article.
-
Cdc2 H1 kinase is negatively regulated by a type 2A phosphatase in the Xenopus early embryonic cell cycle: evidence from the effects of okadaic acid.EMBO J. 1990 Mar;9(3):675-83. doi: 10.1002/j.1460-2075.1990.tb08159.x. EMBO J. 1990. PMID: 2155777 Free PMC article.
-
Expression of protein phosphatases during postnatal development of rabbit heart.Mol Cell Biochem. 2003 Mar;245(1-2):91-8. doi: 10.1023/a:1022865710747. Mol Cell Biochem. 2003. PMID: 12708748
-
Protein phosphatase 2A1 is the major enzyme in vertebrate cell extracts that dephosphorylates several physiological substrates for cyclin-dependent protein kinases.Mol Biol Cell. 1993 Jul;4(7):669-77. doi: 10.1091/mbc.4.7.669. Mol Biol Cell. 1993. PMID: 8400454 Free PMC article.
-
Molecular cloning of rat type 2C (IA) protein phosphatase mRNA.Proc Natl Acad Sci U S A. 1989 Mar;86(6):1796-800. doi: 10.1073/pnas.86.6.1796. Proc Natl Acad Sci U S A. 1989. PMID: 2538815 Free PMC article.
Publication types
MeSH terms
Substances
Grants and funding
LinkOut - more resources
Full Text Sources