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Review
. 2017 Feb 27;8(3):89.
doi: 10.3390/genes8030089.

Epigenetics in Stroke Recovery

Haifa Kassis  1 , Amjad Shehadah  2 , Michael Chopp  3   4 , Zheng Gang Zhang  5
Affiliations
Review

Epigenetics in Stroke Recovery

Haifa Kassis et al. Genes (Basel). .

Abstract

While the death rate from stroke has continually decreased due to interventions in the hyperacute stage of the disease, long-term disability and institutionalization have become common sequelae in the aftermath of stroke. Therefore, identification of new molecular pathways that could be targeted to improve neurological recovery among survivors of stroke is crucial. Epigenetic mechanisms such as post-translational modifications of histone proteins and microRNAs have recently emerged as key regulators of the enhanced plasticity observed during repair processes after stroke. In this review, we highlight the recent advancements in the evolving field of epigenetics in stroke recovery.

Keywords: epigenetics; recovery; stroke.

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Conflict of interest statement

The authors declare no conflict of interest.

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