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. 2017 Mar 6;17(1):22.
doi: 10.1186/s12893-017-0219-9.

Sequential organ failure assessment score predicts mortality after coronary artery bypass grafting

Chih-Hsiang Chang  1   2 , Shao-Wei Chen  3   2 , Pei-Chun Fan  1   2 , Cheng-Chia Lee  1   2 , Huang-Yu Yang  1   2 , Su-Wei Chang  4 , Heng-Chih Pan  5   2 , Feng-Chun Tsai  3   2 , Chih-Wei Yang  1   2 , Yung-Chang Chen  6   7
Affiliations

Sequential organ failure assessment score predicts mortality after coronary artery bypass grafting

Chih-Hsiang Chang et al. BMC Surg. .

Abstract

Background: Mortality after coronary artery bypass grafting (CABG) is generally associated with underlying disease and surgical factors overlooked in preoperative prognostic models. Sequential Organ Failure Assessment (SOFA) and Acute Physiology and Chronic Health Evaluation (APACHE II) scores are widely used in intensive care units for outcome prediction. This study investigated the accuracy of these models in predicting mortality.

Methods: Between January 2010 and April 2013, 483 patients who underwent isolated CABG were enrolled. The clinical characteristics, outcomes, and prognostic model scores of the patients were collected. Discrimination was assessed using the area under the curve approach.

Results: Both SOFA and APACHE II scores were effective for predicting in-hospital mortality. Among the organ systems examined in the SOFA, the cardiac and renal systems were the strongest predictors of CABG mortality. Multivariate analysis identified only the SOFA score as being an independent risk factor for mortality.

Conclusion: In summary, the SOFA score can be used to accurately identify mortality after isolated CABG.

Keywords: Cardiorenal syndrome; Coronary artery by pass grafting; Mortality; Sequential organ failure assessment; Society of thoracic surgeons mortality risk.

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Figures

Fig. 1
Fig. 1
Observed and expected (mean) mortality rates divided by quintiles of expected mortality calculated using the STS risk model, EuroSCORE II, SOFA, and APACHE II
Fig. 2
Fig. 2
Kaplan–Meier survival curves of mortality with log-rank test results according to SOFA score tertiles
See this image and copyright information in PMC

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