Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2017:2017:5163968.
doi: 10.1155/2017/5163968. Epub 2017 Feb 7.

Anthelmintic Resistance of Strongyle Nematodes to Ivermectin and Fenbendazole on Cart Horses in Gondar, Northwest Ethiopia

Zewdu Seyoum  1 , Alemu Zewdu  1 , Shimelis Dagnachew  1 , Basazinew Bogale  1
Affiliations

Anthelmintic Resistance of Strongyle Nematodes to Ivermectin and Fenbendazole on Cart Horses in Gondar, Northwest Ethiopia

Zewdu Seyoum et al. Biomed Res Int. 2017.

Abstract

A study was conducted from November 2015 to April 2016 to determine fenbendazole and ivermectin resistance status of intestinal nematodes of cart horses in Gondar, Northwest Ethiopia. Forty-five strongyle infected animals were used for this study. The animals were randomly allocated into three groups (15 horses per group). Group I was treated with fenbendazole and Group II with ivermectin and Group III was left untreated. Faecal samples were collected from each cart horse before and after treatment. Accordingly, the reduction in the mean fecal egg count at fourteen days of treatment for ivermectin and fenbendazole was 97.25% and 79.4%, respectively. It was significantly different in net egg count between treatment and control groups after treatment. From the study, resistance level was determined for fenbendazole and suspected for ivermectin. In addition, a questionnaire survey was also conducted on 90 selected cart owners to assess their perception on anthelmintics. In the survey, the most available drugs in the study area used by the owners were fenbendazole and ivermectin. Most respondents have no knowledge about drug management techniques. Hence, animal health extension services to create awareness regarding anthelmintic management that plays a key role in reducing the anthelmintic resistance parasites.

PubMed Disclaimer

Conflict of interest statement

The authors declare that there is no conflict of interests regarding the publication of this paper.

Figures

Figure 1
Figure 1
Mean EPG at day 0 and EPG at day 14 with the three experimental groups before and after treatment. EPG D0 = EPG day 0 and EPG D14 = EPG day 14.
See this image and copyright information in PMC

Similar articles

See all similar articles

Cited by

References

    1. Andersen U. V., Howe D. K., Olsen S. N., Nielsen M. K. Recent advances in diagnosing pathogenic equine gastrointestinal helminths: the challenge of prepatent detection. Veterinary Parasitology. 2013;192(1–3):1–9. doi: 10.1016/j.vetpar.2012.11.003. - DOI - PubMed
    1. Wannas H. Y., Dawood K. H., Gassem Gh. Prevalence of gastrointestinal parasites in horses and donkeys in Al Diwaniyah Governorate, AL-Qadisiya. Journal of Veterinary Medical Science. 2012;11(1):841–855.
    1. Martins I. V. F., Verocai G. G., Correia T. R., et al. Survey on control and management practices of equine helminthes infection. Pesquisa Veterinaria Brasileira. 2009;29(3):253–257. doi: 10.1590/S0100-736X2009000300011. - DOI
    1. Umur Ş., Açici M. A survey on helminth infections of equines in the Central Black Sea region, Turkey. Turkish Journal of Veterinary and Animal Sciences. 2009;33(5):373–378. doi: 10.3906/vet-0712-6. - DOI
    1. Brady H. A., Nichols W. T. Drug resistance in equine parasites: an emerging global problem. Journal of Equine Veterinary Science. 2009;29(5):285–295. doi: 10.1016/j.jevs.2009.04.186. - DOI

LinkOut - more resources