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Review
. 2017 Apr;25(2):177-184.
doi: 10.1007/s10787-017-0333-4. Epub 2017 Mar 7.

Update on biosimilars in rheumatology

Affiliations
Review

Update on biosimilars in rheumatology

Adam Rischin et al. Inflammopharmacology. 2017 Apr.

Abstract

Biologic agents have become indispensable in the management of autoimmune disease particularly rheumatological conditions. The lives of countless individuals have been improved following treatment with these drugs. Unfortunately, their cost prohibits more widespread use around the globe. This critical issue has been addressed by the introduction of biosimilars into the market. These therapies have been developed to resemble the originator molecule as closely as possible and to increase competition in the therapy area thus allowing costs to be reduced. Our review is intended to offer an update on biosimilars including logistic considerations on their introduction into routine practice.

Keywords: Biologics; Biosimilars; Efficacy; Health economics; Logistics; Rheumatology; Safety.

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References

    1. Lancet. 1999 Dec 4;354(9194):1932-9 - PubMed
    1. Arthritis Care Res (Hoboken). 2012 Nov;64(11):1649-56 - PubMed
    1. Nat Rev Rheumatol. 2015 Dec;11(12):713-24 - PubMed
    1. J Med Chem. 2010 Dec 23;53(24):8468-84 - PubMed
    1. Expert Rev Clin Immunol. 2014 Aug;10(8):981-3 - PubMed

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