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Review
. 2017;4(1):17-23.
doi: 10.3233/JND-160194.

Cardiac Involvement Classification and Therapeutic Management in Patients with Duchenne Muscular Dystrophy

Abdallah Fayssoil  1   2 , Soumeth Abasse  3 , Katy Silverston  4
Affiliations
Free PMC article
Review

Cardiac Involvement Classification and Therapeutic Management in Patients with Duchenne Muscular Dystrophy

Abdallah Fayssoil et al. J Neuromuscul Dis. 2017.
Free PMC article

Abstract

Duchenne muscular dystrophy (DMD) is an inherited myogenic disorder due to mutations in the dystrophin gene on chromosome Xp21.1. The clinical picture included peripheral muscle weakness, cardiomyopathy and chronic respiratory insufficiency. In this paper, the authors review cardiac involvement in patients with DMD, propose a cardiac impairment classification and discuss therapeutic management options.

Keywords: CMR; Duchenne muscular dystrophy; cardiomyopathy; classification; echocardiography.

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Figures

Fig.1
Fig.1
Pathophysiology of heart failure in DMD. LVEF: left ventricular ejection fraction. LV: left ventricle. RAA: renin angiotensin aldosterone.
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Comment in

References

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