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. 1988 Jan;8(1):461-5.
doi: 10.1128/mcb.8.1.461-465.1988.

Phosphorylation of p53 in normal and simian virus 40-transformed NIH 3T3 cells

D W Meek  1 , W Eckhart
Affiliations

Phosphorylation of p53 in normal and simian virus 40-transformed NIH 3T3 cells

D W Meek et al. Mol Cell Biol. 1988 Jan.

Abstract

We observed six major tryptic phosphopeptides in p53 from simian virus 40-transformed and normal NIH 3T3 cells. Analyses of the phosphopeptides indicated that serines 37, 310 and/or 312, 389 and one or more of serines 7, 9, 12, 18, and 23 were phosphorylated. Phosphorylation of serines 310 and/or 312 was twofold higher in the simian virus 40-transformed cells as compared with that in normal NIH 3T3 cells.

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