Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2017 Mar 13;27(1):18.
doi: 10.1038/s41533-017-0019-9.

Raising awareness of bronchiectasis in primary care: overview of diagnosis and management strategies in adults

Affiliations
Review

Raising awareness of bronchiectasis in primary care: overview of diagnosis and management strategies in adults

James D Chalmers et al. NPJ Prim Care Respir Med. .

Abstract

Bronchiectasis is a chronic lung disease characterised by recurrent infection, inflammation, persistent cough and sputum production. The disease is increasing in prevalence, requiring a greater awareness of the disease across primary and secondary care. Mild and moderate cases of bronchiectasis in adults can often be managed by primary care clinicians. Initial assessments and long-term treatment plans that include both pharmacological and non-pharmacological treatments, however, should be undertaken in collaboration with a secondary care team that includes physiotherapists and specialists in respiratory medicine. Bronchiectasis is often identified in patients with other lung diseases, such as chronic obstructive pulmonary disease, asthma, and in a lesser but not insignificant number of patients with other inflammatory diseases, such as rheumatoid arthritis and inflammatory bowel disease. Overall goals of therapy are to prevent exacerbations, improve symptoms, improve quality of life and preserve lung function. Prompt treatment of exacerbations with antibiotic therapy is important to limit the impact of exacerbations on quality of life and lung function decline. Patient education and cooperation with health-care providers to implement treatment plans are key to successful disease management. It is important for the primary care provider to work with secondary care providers to develop an individualised treatment plan to optimise care with the goal to delay disease progression. Here, we review the diagnosis and treatment of bronchiectasis with a focus on practical considerations that will be useful to primary care.

PubMed Disclaimer

Figures

Fig. 1
Fig. 1
Vicious cycle hypothesis of bronchiectasis,
Fig. 2
Fig. 2
Example high-resolution chest computed tomography images of bronchiectasis. a Cylindrical bronchiectasis; b longitudinal or varicose bronchiectasis
Fig. 3
Fig. 3
Bronchiectasis disease management. COPD, chronic obstructive pulmonary disease
Fig. 4
Fig. 4
Considerations for the management of bronchiectasis in a patient with worsening symptoms in primary care. ABPA, allergic bronchopulmonary aspergillosis; BSI, bronchiectasis severity index; HRCT, high-resolution chest computed tomography; NTM, non-tuberculous Mycobacteria

References

    1. Chalmers JD, Hill AT. Mechanisms of immune dysfunction and bacterial persistence in non-cystic fibrosis bronchiectasis. Mol. Immunol. . 2013;55:27–34. doi: 10.1016/j.molimm.2012.09.011. - DOI - PubMed
    1. Pasteur, M. C., Bilton, D.&Hill, A. T.; on behalf of the British Thoracic Society Bronchiectasis (non-CF) Guideline Group. British Thoracic Society guideline for non-CF bronchiectasis. Thorax65, i1–58 (2010). - PubMed
    1. Chalmers JD, Elborn JS. Reclaiming the name ‘bronchiectasis’. Thorax . 2015;70:399–400. doi: 10.1136/thoraxjnl-2015-206956. - DOI - PubMed
    1. Cole PJ, Wilson R. Host-microbial interrelationships in respiratory infection. Chest . 1989;95:217S–221S. doi: 10.1378/chest.95.3_Supplement.217S. - DOI
    1. Chalmers JD, Aliberti S, Blasi F. Management of bronchiectasis in adults. Eur. Respir. J. . 2015;45:1446–1462. doi: 10.1183/09031936.00119114. - DOI - PubMed

MeSH terms