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Case Reports
. 2017:2017:8541078.
doi: 10.1155/2017/8541078. Epub 2017 Feb 8.

Simultaneous Papillary Carcinoma in Thyroglossal Duct Cyst and Thyroid

Gustavo Cancela E Penna  1 , Henrique Gomes Mendes  2 , Adele O Kraft  3 , Cynthia Koeppel Berenstein  4 , Bernardo Fonseca  5 , Wagner José Martorina  6 , Andreise Laurian N R de Souza  7 , Gustavo Meyer de Moraes  8 , Kamilla Maria Araújo Brandão Rajão  9 , Bárbara Érika Caldeira Araújo Sousa  10
Affiliations
Case Reports

Simultaneous Papillary Carcinoma in Thyroglossal Duct Cyst and Thyroid

Gustavo Cancela E Penna et al. Case Rep Endocrinol. 2017.

Abstract

Thyroglossal duct cyst (TDC) is a cystic expansion of a remnant of the thyroglossal duct tract. Carcinomas in the TDC are extremely rare and are usually an incidental finding after the Sistrunk procedure. In this report, an unusual case of a 36-year-old woman with concurrent papillary thyroid carcinoma arising in the TDC and on the thyroid gland is presented, followed by a discussion of the controversies surrounding the possible origins of a papillary carcinoma in the TDC, as well as the current management options.

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Conflict of interest statement

The authors declare that there is no conflict of interests that could be perceived as prejudicing the impartiality of the research reported.

Figures

Figure 1
Figure 1
Sonography shows an image suggestive of thyroglossal duct cyst containing debris and an eccentric small hyperechoic solid area.
Figure 2
Figure 2
Thyroglossal duct cyst carcinoma. (a) and (b) Low power view of the cyst containing the papillary carcinoma (HE, 40x). (c) The papillae were sometimes edematous (HE, 40x). (d) The tumor had papillae, but also some follicles (HE, 100x). (e) Nuclei with pseudoinclusions (arrow) and ground glass appearance (stars) (HE, 400x). (f) Nuclear pseudoinclusion (HE, 400x). (g) Nuclear pseudoinclusion (arrow) (HE, 1000x). (h) Nuclear groove (arrow) (HE, 1000x).
See this image and copyright information in PMC

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