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Review
. 2017 Jun;19(3):357-362.
doi: 10.1007/s11307-017-1054-1.

Optical Surgical Navigation for Precision in Tumor Resections

Stefan Harmsen  1 , Nutte Teraphongphom  2 , Michael F Tweedle  3 , James P Basilion  4   5   6 , Eben L Rosenthal  7   8
Affiliations
Review

Optical Surgical Navigation for Precision in Tumor Resections

Stefan Harmsen et al. Mol Imaging Biol. 2017 Jun.

Abstract

Optical imaging methods have significant potential as effective intraoperative tools to visualize tissues, cells, and biochemical events aimed at objective assessment of the tumor margin and guiding the surgeon to adequately resect the tumor while sparing critical tissues. The wide variety of approaches to guide resection, the range of parameters that they detect, and the interdisciplinary nature involving biology, chemistry, engineering, and medicine suggested that there was a need for an organization that could review, discuss, refine, and help prioritize methods to optimize patient care and pharmaceutical and instrument development. To address these issues, the World Molecular Imaging Society created the Optical Surgical Navigation (OSN) interest group to bring together scientists, engineers, and surgeons to develop the field to benefit patients. Here, we provide an overview of approaches currently under clinical investigation for optical surgical navigation and offer our perspective on upcoming strategies.

Keywords: Image guidance; Oncology; Optical navigation; Probes; Surgery.

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Conflict of interest statement

Compliance with Ethical Standards

Conflict of Interests

S.H., N.T., M.F.T., and E.L.R. declare no conflicts of interests. J.P.B. has an interest in Akrotome Imaging Inc., a company developing probes in this space, and consults for Vergent Biosciences and LightPoint Medical Ltd.

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