Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2017 Jun 1;2(6):699-700.
doi: 10.1001/jamacardio.2016.5993.

Time-Related Microcirculatory Dysfunction in Patients With Takotsubo Cardiomyopathy

Fernando Rivero  1 , Javier Cuesta  1 , Marcos García-Guimaraes  1 , Teresa Bastante  1 , Teresa Alvarado  1 , Paula Antuña  1 , Fernando Alfonso  1
Affiliations

Time-Related Microcirculatory Dysfunction in Patients With Takotsubo Cardiomyopathy

Fernando Rivero et al. JAMA Cardiol. .

Abstract

This study assesses whether there is a time-dependent trend in microvascular damage in patients presenting with takotsubo cardiomyopathy by invasively measuring the index of microvascular resistance.

PubMed Disclaimer

Conflict of interest statement

Conflict of Interest Disclosures: All authors have completed and submitted the ICMJE Form for Disclosure of Potential Conflicts of Interest and none were reported.

Figures

Figure.
Figure.. Time-Related Evolution of Microvascular Dysfunction in Takotsubo Myocardiopathy
Time represents the time since symptom onset to index of microvascular resistance (IMR) measurement. The solid line indicates the regression line; the dotted line, the prespecified IMR threshold; the points, each individual IMR measurement.
See this image and copyright information in PMC

References

    1. Tsuchihashi K, Ueshima K, Uchida T, et al. ; Angina Pectoris-Myocardial Infarction Investigations in Japan . Transient left ventricular apical ballooning without coronary artery stenosis: a novel heart syndrome mimicking acute myocardial infarction. J Am Coll Cardiol. 2001;38(1):11-18. - PubMed
    1. Kim HS, Tremmel JA, Nam CW, et al. . Quantitative comparison of microcirculatory dysfunction in patients with stress cardiomyopathy and ST-segment elevation myocardial infarction. J Am Coll Cardiol. 2011;58(23):2430-2431. - PubMed
    1. Prasad A, Lerman A, Rihal CS. Apical ballooning syndrome (tako-tsubo or stress cardiomyopathy): a mimic of acute myocardial infarction. Am Heart J. 2008;155(3):408-417. - PubMed
    1. Melikian N, Vercauteren S, Fearon WF, et al. . Quantitative assessment of coronary microvascular function in patients with and without epicardial atherosclerosis. EuroIntervention. 2010;5(8):939-945. - PubMed
    1. Galiuto L, De Caterina AR, Porfidia A, et al. . Reversible coronary microvascular dysfunction: a common pathogenetic mechanism in apical ballooning or tako-tsubo syndrome. Eur Heart J. 2010;31(11):1319-1327. - PubMed

LinkOut - more resources