Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2017 Feb;5(4):70.
doi: 10.21037/atm.2016.11.47.

Cannulation techniques for extracorporeal life support

Affiliations
Review

Cannulation techniques for extracorporeal life support

Evgeny Pavlushkov et al. Ann Transl Med. 2017 Feb.

Abstract

The article reviews cannulation strategy for different modes of extracorporeal life support. Technical aspects, pitfalls and complications are discussed for central and peripheral extracorporeal membrane oxygenation (VA, VV, VAV, VVA), biventricular assist device support and extracorporeal CO2 removal.

Keywords: BiVAD; Cannulation; ECLS; ECMO; biventricular assist device; extracorporeal CO2 removal; extracorporeal life support; extracorporeal membrane oxygenation.

PubMed Disclaimer

Conflict of interest statement

Conflicts of Interest: The authors have no conflicts of interest to declare.

Figures

Figure 1
Figure 1
Diagram of central ECMO: the blood is drained via a large venous cannula from the right atrium under negative pressure and transferred through oxygenator, following which returned to the body via a cannula into the ascending aorta. The cannula can be tunnelled under the skin and chest closed if longer than few days’ support is anticipated.
Figure 2
Figure 2
Cannulae for BiVAD tunnelled and ready for cannulation.
Figure 3
Figure 3
Peripheral VA ECMO cannulation: the blood is drained from the IVC via femoral cannulation. It passes through a centrifugal pump and oxygenator and is returned to the patient via femoral artery. On this diagram, a reperfusion line is used to ensure distal limb perfusion.
Figure 4
Figure 4
Watershed phenomenon during veno-arterial ECMO visualized by computed tomography. Antegrade blood flow (low contrast) from the heart competes with retrograde blood flow (high contrast) from the ECMO in the aorta, resulting in a watershed phenomenon (arrowhead). Here computed tomography of a patient with pulmonary embolism and reduced cardiac output demonstrates a rather proximal watershed, leading to perfusion of the right carotid artery with “heart blood” (dark) and the left carotid artery with “ECMO blood” (bright, arrows). Upper panel sagittal oblique maximum intensity projection (MIP), middle panel coronal oblique MIP, lower panel transverse plane (14).
Figure 5
Figure 5
Veno-venous ECMO: blood is drained from the IVC and passes through an oxygenator, then returned to the venous system via the right atrium.

References

    1. Extracorporeal life support organization (ELSO guidelines). 2013. Available online: http://www.elso.org/resources/Guidelines.aspx
    1. Murphy DA, Hockings LE, Andrews RK, et al. Extracorporeal membrane oxygenation-hemostatic complications. Transfus Med Rev 2015;29:90-101. 10.1016/j.tmrv.2014.12.001 - DOI - PubMed
    1. Saeed D, Stosik H, Islamovic M, et al. Femoro-femoral versus atrio-aortic extracorporeal membrane oxygenation: selecting the ideal cannulation technique. Artif Organs 2014;38:549-55. 10.1111/aor.12245 - DOI - PubMed
    1. Kohler K, Valchanov K, Nias G, et al. ECMO cannula review. Perfusion 2013;28:114-24. 10.1177/0267659112468014 - DOI - PubMed
    1. Schlensak C, Schibilsky D, Siepe M, et al. Biventricular cannulation is superior regarding hemodynamics and organ recovery in patients on biventricular assist device support. J Heart Lung Transplant 2011;30:1011-7. 10.1016/j.healun.2011.02.013 - DOI - PubMed