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Editorial
. 2017 Feb 15:4:10.
doi: 10.21037/sci.2017.01.04. eCollection 2017.

Bringing light into gene regulation in hematopoietic stem cells by the Mediator complex

Christian Kosan  1 , Maren Godmann  1
Affiliations
Editorial

Bringing light into gene regulation in hematopoietic stem cells by the Mediator complex

Christian Kosan et al. Stem Cell Investig. .
No abstract available

PubMed Disclaimer

Conflict of interest statement

Conflicts of Interest: The authors have no conflicts of interest to declare.

Comment on

  • MED12 Regulates HSC-Specific Enhancers Independently of Mediator Kinase Activity to Control Hematopoiesis.
    Aranda-Orgilles B, Saldaña-Meyer R, Wang E, Trompouki E, Fassl A, Lau S, Mullenders J, Rocha PP, Raviram R, Guillamot M, Sánchez-Díaz M, Wang K, Kayembe C, Zhang N, Amoasii L, Choudhuri A, Skok JA, Schober M, Reinberg D, Sicinski P, Schrewe H, Tsirigos A, Zon LI, Aifantis I. Aranda-Orgilles B, et al. Cell Stem Cell. 2016 Dec 1;19(6):784-799. doi: 10.1016/j.stem.2016.08.004. Epub 2016 Aug 25. Cell Stem Cell. 2016. PMID: 27570068 Free PMC article.

References

    1. Kosan C, Godmann M. Genetic and Epigenetic Mechanisms That Maintain Hematopoietic Stem Cell Function. Stem Cells Int 2016;2016:5178965. 10.1155/2016/5178965 - DOI - PMC - PubMed
    1. Wilson A, Laurenti E, Oser G, et al. Hematopoietic stem cells reversibly switch from dormancy to self-renewal during homeostasis and repair. Cell 2008;135:1118-29. 10.1016/j.cell.2008.10.048 - DOI - PubMed
    1. Allen BL, Taatjes DJ. The Mediator complex: a central integrator of transcription. Nat Rev Mol Cell Biol 2015;16:155-66. 10.1038/nrm3951 - DOI - PMC - PubMed
    1. Taatjes DJ, Näär AM, Andel F, 3rd, et al. Structure, function, and activator-induced conformations of the CRSP coactivator. Science 2002;295:1058-62. 10.1126/science.1065249 - DOI - PubMed
    1. Aranda-Orgilles B, Saldaña-Meyer R, Wang E, et al. MED12 Regulates HSC-Specific Enhancers Independently of Mediator Kinase Activity to Control Hematopoiesis. Cell Stem Cell 2016;19:784-99. 10.1016/j.stem.2016.08.004 - DOI - PMC - PubMed

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