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Comparative Study
. 1988 Jan;207(1):21-5.
doi: 10.1097/00000658-198801000-00005.

Orthotopic liver transplantation for primary sclerosing cholangitis

J W Marsh Jr  1 , S Iwatsuki, L Makowka, C O Esquivel, R D Gordon, S Todo, A Tzakis, C Miller, D Van Thiel, T E Starzl
Affiliations
Comparative Study

Orthotopic liver transplantation for primary sclerosing cholangitis

J W Marsh Jr et al. Ann Surg. 1988 Jan.

Abstract

The incidence or diagnostic rate of sclerosing cholangitis is increasing. Because of the lack of effective medical or surgical therapy for patients with end-stage liver disease and sclerosing cholangitis, results with orthotopic liver transplantation were examined. The results of 55 consecutive liver replacements for this disease were reviewed. The 1- and 2-year actuarial survival rates are 71% and 57%, respectively. Orthotopic liver transplantation for end-stage liver disease from sclerosing cholangitis has emerged as the most effective therapy.

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