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. 1987 Jun;65(6):525-8.
doi: 10.1139/o87-067.

A neutral sphingomyelinase in spermatozoal plasma membranes

V T Hinkovska  1 , D H Petkova, K S Koumanov
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A neutral sphingomyelinase in spermatozoal plasma membranes

V T Hinkovska et al. Biochem Cell Biol. 1987 Jun.

Abstract

A highly active neutral sphingomyelinase was observed for the first time in ram spermatozoal plasma membranes. The optimal conditions for the enzyme activity are pH 7.4, 40 mM MgCl2, 40 min of incubation, and 267 nmol sphingomyelin. Ca2+ and cholesterol were found to inhibit sphingomyelinase activity.

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