Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Comment
. 2017 Mar 8;21(3):312-314.
doi: 10.1016/j.chom.2017.02.011.

Unsweetened IgG Is Bad for Dengue Patients

Shee-Mei Lok  1
Affiliations
Free article
Comment

Unsweetened IgG Is Bad for Dengue Patients

Shee-Mei Lok. Cell Host Microbe. .
Free article

Abstract

Dengue hemorrhagic fever is shown to correlate with secondary infection with a virus serotype different from the previous infection. However, only a small fraction of secondary infections leads to hemorrhagic fever. A recent Science paper suggests that the fucosylation state and isotype of IgGs elicited in patients may enhance disease severity.

Keywords: IgG; dengue; dengue hemorrhagic fever; enhancement of disease; fucosylation of IgG; platelet depletion.

PubMed Disclaimer

Comment on

LinkOut - more resources