Prevalence and pattern of birth defects in a tertiary health facility in the Niger Delta area of Nigeria
- PMID: 28280393
- PMCID: PMC5339003
- DOI: 10.2147/IJWH.S108905
Prevalence and pattern of birth defects in a tertiary health facility in the Niger Delta area of Nigeria
Abstract
Objective: To ascertain the prevalence and pattern of congenital abnormalities that are peculiar to the Niger Delta area of Nigeria.
Methods: This is a descriptive retrospective cross-sectional study. It involved data from the labor ward and neonatal birth registers of the University of Port Harcourt Teaching Hospital on the total number of births and the babies that were delivered with major birth defects between August 2011 and December 2014. We also conducted a statistical comparison of the prevalence of congenital abnormalities in the Niger Delta with that in other regions of Nigeria and the developed world of Europe.
Results: Out of the 7,670 deliveries that occurred, 159 maternities had babies with major birth defects giving a prevalence of 20.73 cases per 1,000 live births. This figure is far more than that which was obtained in other regions of Nigeria -4.15:cases per 1,000 live births in the South East (P<0.001), 15.84:1,000 in the South West (P<0.01), and 5.51:1,000 in the North East (P<0.001). Eighty-five (53.46%) of the defects occurred in 1,681 unbooked patients, while 74 (46.54%) happened in 5,989 booked maternities (P<0.001). The predominant abnormalities were those of the central nervous system at 27.0%, gastrointestinal system 11.95%, cardiovascular system 10.69%, anterior abdominal wall 8.18%, skeleton 6.29%, and chromosomal abnormalities at 5.66%.
Conclusion: The prevalence of major birth defects at the University of Port Harcourt Teaching Hospital was 20.73 cases per 1,000 live births and it was more in the unbooked than the booked maternities. All body systems were affected with those of the central nervous system predominating at 27.0% of the total diagnosed defects.
Keywords: Niger Delta; Port Harcourt; birth defects; booked; congenital abnormalities; maternity; unbooked.
Conflict of interest statement
Disclosure The authors report no conflicts of interest in this work.
References
-
- WHO . Congenital Anomalies. (Fact sheet No. 370). Updated April 2015.
-
- MOD (March of Dimes) The March of Dimes Global Report on Birth Defects: The Hidden Toll of Dying and Disabled Children. White Plains: NY: March of Dimes Birth Defects Foundation; 2006. Available from: http://www.marchofdimes.com/MOD-Report-PF.pdf.
-
- Turnpenny P, Ellard S. Emery’s Elements of Medical Genetics. 12th ed. Edinburgh, UK: Elsevier Churchill Livingstone; 2005.
-
- World Bank Country Classification. 2005. [Accessed October 16, 2008]. Available from: www.worldbank.Org/data/countryclass/countryclass.html.
-
- Ekanem TB, Okon DE, Akpantah AO, Mesembe OE, Eluwa MA, Ekong MB. Prevalence of congenital malformations in Cross River and Akwa Ibom states of Nigeria from 1980–2003. Congenit Anom (Kyoto) 2008;48(4):167–170. - PubMed
LinkOut - more resources
Full Text Sources
Other Literature Sources
