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. 2017 Oct;31(19):2245-2249.
doi: 10.1080/14786419.2017.1299730. Epub 2017 Mar 10.

α-pyrone derivatives from a marine actinomycete Nocardiopsis sp. YIM M13066

Xiao-Mei Zhang  1 , Ming-Wei Sun  2 , Hui Shi  2 , Chun-Hua Lu  2
Affiliations

α-pyrone derivatives from a marine actinomycete Nocardiopsis sp. YIM M13066

Xiao-Mei Zhang et al. Nat Prod Res. 2017 Oct.

Abstract

Five new α-pyrones namely nocapyrones O-S (2-6) and nocapyrone F (1) were isolated from a deep-sea sediment strain Nocardiopsis sp. YIM M13066. Their structures were elucidated by their NMR spectroscopic data, HR-ESI-MS and crystal X-ray diffraction. Their cytotoxic activities against H1299, HeLa, HL7702, MCF-7, PC3 and U251 cell lines were evaluated.

Keywords: crystal X-ray diffraction; cytotoxic activities; nocapyrones O-S; spectroscopic data; α-pyrones.

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