Review
doi: 10.1097/IIO.0000000000000170.
Effects of Aging in Dry Eye
- PMID: 28282314
- PMCID: PMC5347479
- DOI: 10.1097/IIO.0000000000000170
Item in Clipboard
Review
Effects of Aging in Dry Eye
Int Ophthalmol Clin.
2017 Spring.
Abstract
Dry eye affects millions of people worldwide and causes eye well recognized risk factors for dry eye. Anatomical and inflammation-induced age-related changes affect all components of the lacrimal gland functional unit, inclusive of lacrimal gland, conjunctiva, meibomian gland and compromise ocular surface health. There is increased evidence that inflammation plays a role in dry eye. This review will summarize the current knowledge about aging and dry eye, inclusive of lessons learned from animal models and promising therapies.
Figures
Aging induces profound systemic changes but also changes the lacrimal gland functional unit.
Similar articles
-
Potential Role of Oxidative Stress in Ocular Surface Inflammation and Dry Eye Disease.Invest Ophthalmol Vis Sci. 2018 Nov 1;59(14):DES163-DES168. doi: 10.1167/iovs.17-23402. Invest Ophthalmol Vis Sci. 2018. PMID: 30481822 Review.
-
[Pathogenesis of dry eye].Ophthalmologe. 2014 May;111(5):411. Ophthalmologe. 2014. PMID: 24959649 German. No abstract available.
-
The antiaging approach for the treatment of dry eye.Cornea. 2012 Nov;31 Suppl 1:S3-8. doi: 10.1097/ICO.0b013e31826a05a8. Cornea. 2012. PMID: 23038031 Review.
-
Tearful relations: oxidative stress, inflammation and eye diseases.Arq Bras Oftalmol. 2008 Nov-Dec;71(6 Suppl):72-9. doi: 10.1590/s0004-27492008000700015. Arq Bras Oftalmol. 2008. PMID: 19274416 Review.
-
[Oxidative stress and inflammation: hypothesis for the mechanism of aging].Nippon Ganka Gakkai Zasshi. 2007 Mar;111(3):193-205; discussion 206. Nippon Ganka Gakkai Zasshi. 2007. PMID: 17402562 Review. Japanese.
Cited by
-
Age Associations with Dry Eye Clinical Signs and Symptoms in the Dry Eye Assessment and Management (DREAM) Study.Ophthalmol Sci. 2023 Jan 12;3(2):100270. doi: 10.1016/j.xops.2023.100270. eCollection 2023 Jun. Ophthalmol Sci. 2023. PMID: 36846104 Free PMC article.
-
Is dry eye disease the same in young and old patients? A narrative review of the literature.BMC Ophthalmol. 2022 Feb 22;22(1):85. doi: 10.1186/s12886-022-02269-2. BMC Ophthalmol. 2022. PMID: 35193524 Free PMC article. Review.
-
The association of subjective vision with objectively measured intensity-specific physical activity and bout-specific sedentary behavior among community-dwelling older adults in Japan.Jpn J Ophthalmol. 2023 Mar;67(2):164-174. doi: 10.1007/s10384-023-00977-w. Epub 2023 Jan 28. Jpn J Ophthalmol. 2023. PMID: 36708419
-
The Protective Effect of Oral Application of Corni Fructus on the Disorders of the Cornea, Conjunctiva, Lacrimal Gland and Retina by Topical Particulate Matter 2.5.Nutrients. 2021 Aug 27;13(9):2986. doi: 10.3390/nu13092986. Nutrients. 2021. PMID: 34578864 Free PMC article.
-
The health-related quality of life in patients with dry eye syndrome: a cross-sectional study in Thailand.BMC Ophthalmol. 2024 Dec 18;24(1):539. doi: 10.1186/s12886-024-03808-9. BMC Ophthalmol. 2024. PMID: 39695504 Free PMC article.
References
-
- Schein OD, Munoz B, Tielsch JM, Bandeen-Roche K, West S. Prevalence of dry eye among the elderly. Am J Ophthalmol. 1997;124:723–728. - PubMed
-
- Schein OD, Tiesch JM, Munoz B, Bandeen-Roche K, West S. Relation between signs and symptoms of dry eye in the elderly. A population-based perspective. Ophthalmology. 1997;104:1395–1401. - PubMed
-
- Moss SE, Klein R, Klein BE. Incidence of dry eye in an older population. Arch Ophthalmol. 2004;122:369–373. - PubMed
-
- Schaumberg DA, Sullivan DA, Buring JE, Dana MR. Prevalence of dry eye syndrome among US women. Am J Ophthalmol. 2003;136:318–326. - PubMed
Publication types
MeSH terms
Grants and funding
LinkOut - more resources
Full Text Sources
Other Literature Sources
Medical
