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Review
. 2017 Spring;57(2):47-64.
doi: 10.1097/IIO.0000000000000170.

Effects of Aging in Dry Eye

Cintia S de Paiva
Review

Effects of Aging in Dry Eye

Cintia S de Paiva. Int Ophthalmol Clin. 2017 Spring.

Abstract

Dry eye affects millions of people worldwide and causes eye well recognized risk factors for dry eye. Anatomical and inflammation-induced age-related changes affect all components of the lacrimal gland functional unit, inclusive of lacrimal gland, conjunctiva, meibomian gland and compromise ocular surface health. There is increased evidence that inflammation plays a role in dry eye. This review will summarize the current knowledge about aging and dry eye, inclusive of lessons learned from animal models and promising therapies.

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Figures

Figure 1
Figure 1
Aging induces profound systemic changes but also changes the lacrimal gland functional unit.
See this image and copyright information in PMC

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