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. 1987;87(5):439-43.
doi: 10.1007/BF00496815.

Diurnal variation in 5'-nucleotidase activity in rat liver. A quantitative histochemical study

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Diurnal variation in 5'-nucleotidase activity in rat liver. A quantitative histochemical study

W M Frederiks et al. Histochemistry. 1987.

Abstract

The diurnal variation of 5'-nucleotidase activity in periportal and pericentral areas of rat liver parenchyma has been determined with quantitative histochemical means. 5'-Nucleotidase activity was estimated using microdensitometry in cryostat sections after being incubated with a medium according to Wachstein and Meisel (1957). It appeared that 5'-nucleotidase activity was significantly higher in pericentral areas than in periportal areas throughout the daily cycle and showed a maximum at the end of the light period. It was concluded that 5'-nucleotidase activity may be related with the capacity to diminish messenger RNA resulting in protein breakdown.

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