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Comment
. 2017 Mar 9;168(6):947-948.
doi: 10.1016/j.cell.2017.02.029.

Gel or Die: Phase Separation as a Survival Strategy

Sonja Kroschwald  1 , Simon Alberti  2
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Gel or Die: Phase Separation as a Survival Strategy

Sonja Kroschwald et al. Cell. .
Free article

Abstract

Stress conditions trigger protein assembly by demixing from the cytoplasm, but the biological significance is still unclear. In this issue of Cell, Riback et al. report that the yeast poly(A)-binding protein 1 (Pab1) is a phase-separating stress sensor that boosts organismal fitness under physiological stress conditions.

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