Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2017 Jun 1:236:82-84.
doi: 10.1016/j.ijcard.2017.02.128. Epub 2017 Feb 27.

Palaeopathology of the earlobe crease (Frank's sign): New insights from Renaissance art

Affiliations

Palaeopathology of the earlobe crease (Frank's sign): New insights from Renaissance art

Francesco M Galassi et al. Int J Cardiol. .

Erratum in

Abstract

Several studies have associated the earlobe crease sign, discovered by Sanders T. Frank in 1973, with cardiovascular pathology, yet very few studies have focused on the antiquity of this trait, with the most ancient one thought to date back to the Roman Emperor Hadrian (76-138CE). This article presents two more cases from the Italian Renaissance in the works of the artist Andrea Mantegna (1431-1506) and examines them in a multidisciplinary fashion.

Keywords: Cardiovascular pathology; Earlobe crease; Frank's sign; Mantegna; Palaeopathology; Prevention; Renaissance.

PubMed Disclaimer

Similar articles

Cited by

Publication types

LinkOut - more resources