Specific amino acid substitutions are not required for transformation by v-myb of avian myeloblastosis virus
- PMID: 2828660
- PMCID: PMC253675
- DOI: 10.1128/JVI.62.3.1093-1096.1988
Specific amino acid substitutions are not required for transformation by v-myb of avian myeloblastosis virus
Abstract
The protein product of the v-myb oncogene of avian myeloblastosis virus, p48v-myb, differs structurally in several ways from its normal cellular homolog, p75c-myb. We demonstrated that the 11 specific amino acid substitutions found in two independent molecular clones of this virus were not required for the transformation of myeloblasts by v-myb.
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