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. 1987;176(6):315-27.
doi: 10.1007/BF00194891.

Antibody reactivity with Skinner HSV vaccine

E M Muniu  1 , J Durham, D Shariff, C E Hartley, A Fuller, J Melling, C Wiblin, G Wilkins, A Buchan, G R Skinner
Affiliations

Antibody reactivity with Skinner HSV vaccine

E M Muniu et al. Med Microbiol Immunol. 1987.

Abstract

Antibody reactivity against herpes simplex virus (HSV) was investigated in 15 subjects who received three subcutaneous immunisations with Skinner HSV vaccine. Humoral antibody responses were detected against type 1 HSV in every subject and against type 2 HSV in all but one subject; immuno-precipitating antibody responses were infrequently detected. There was no antibody reactivity against host-cell (MRC-5), foetal calf serum or rubella virus antigen. None of the vaccinated subjects developed clinical evidence of herpes genitalis.

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