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. 2016;29(95):52-53.

Squamous cell carcinoma of the conjunctiva

Stephen Gichuhi  1 , Mandeep S Sagoo  2
Affiliations

Squamous cell carcinoma of the conjunctiva

Stephen Gichuhi et al. Community Eye Health. 2016.
No abstract available

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Figures

Figure 1.
Figure 1.
A range of OSSN presentations seen in East Africa.
Figure 2.
Figure 2.
Conjunctival lesions before and after staining with 0.05% toluidine blue. The pictures in the left column are before staining and those on the right after staining. Images A and B show moderately differentiated squamous cell carcinoma, with deep royal blue staining. C and D show actinic keratosis, with mixed staining (margin and parts of the lesion).
Figure 3.
Figure 3.
Picture A shows the pre-operative appearance of a lesion in a 32-year-old woman. She was HIV infected with a CD4 count of 69 cellsμ/L. The lesion was excised with a 4 mm margin. She was given topical Gentamycin and Prednisolone drops 4 times daily for 3 weeks. Histopathology showed moderately differentiated squamous cell carcinoma. She was given 1% 5FU drops to apply 4 times daily for 4 weeks. (B) shows the eye about a year later; the lesion had not recurred.
See this image and copyright information in PMC

References

    1. Gichuhi S, Sagoo MS, Weiss HA, Burton MJ. Epidemiology of ocular surface squamous neoplasia in Africa. Trop Med Int Health 2013; 18(12): 1424–43. - PMC - PubMed
    1. Tunc M, Char DH, Crawford B, Miller T. Intraepithelial and invasive squamous cell carcinoma of the conjunctiva: analysis of 60 cases. Br J Ophthalmol 1999; 83(1): 98–103. - PMC - PubMed
    1. Waddell KM, Downing RG, Lucas SB, Newton R. Corneo-conjunctival carcinoma in Uganda. Eye (Lond) 2006; 20(8): 893–9. - PubMed
    1. Gichuhi S, Macharia E, Kabiru J, et al. Toluidine Blue 0.05% Vital Staining for the Diagnosis of Ocular Surface Squamous Neoplasia in Kenya. JAMA Ophthalmol 2015; 133(11): 1314–21. - PMC - PubMed
    1. Gichuhi S, Macharia E, Kabiru J, et al. Topical fluorouracil after surgery for ocular surface squamous neoplasia in Kenya: a randomised, double-blind, placebo-controlled trial. Lancet Glob Health 2016; 4(6): e378–e85. - PMC - PubMed

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