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Observational Study
. 2017 Mar 14;18(1):108.
doi: 10.1186/s12891-017-1465-9.

Sex differences in gout characteristics: tailoring care for women and men

Leslie R Harrold  1 , Carol J Etzel  2   3 , Allan Gibofsky  4 , Joel M Kremer  5 , Michael H Pillinger  6 , Kenneth G Saag  7 , Naomi Schlesinger  8 , Robert Terkeltaub  9 , Vanessa Cox  2 , Jeffrey D Greenberg  2   6
Affiliations
Observational Study

Sex differences in gout characteristics: tailoring care for women and men

Leslie R Harrold et al. BMC Musculoskelet Disord. .

Abstract

Background: To characterize the differences between women and men with gout.

Methods: We analyzed a US national cohort of gout patients cared for by rheumatologists.

Results: Compared with the 1012 men with gout, women with gout (n = 262) were older (71 vs. 61 years, p < 0.001) and had a greater burden of comorbid conditions (p < 0.001 for hypertension, diabetes, renal disease and obesity). Risk factors for gout differed with women more often taking diuretics (p < 0.001), while men more frequently had dietary triggers (p < 0.05).

Conclusions: The profiles of women and men with gout are markedly different, suggesting a need to tailor treatment recommendations.

Keywords: Comorbidity; Gender; Gout; Quality of Care.

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Figures

Fig. 1
Fig. 1
Comparison of the dietary factors that influence gout in women and men. The results are adjusted for age, BMI, duration of gout, comorbidity burden [hypertension, diabetes, renal disease, hyperlipidemia], HCTZ use, other diuretic use and current use of a urate-lowering drug
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