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Comment
. 2017 Feb 28:8:319.
doi: 10.3389/fmicb.2017.00319. eCollection 2017.

Commentary: Type I CRISPR-Cas targets endogenous genes and regulates virulence to evade mammalian host immunity

Hanna Müller-Esparza  1 , Lennart Randau  1
Affiliations
Comment

Commentary: Type I CRISPR-Cas targets endogenous genes and regulates virulence to evade mammalian host immunity

Hanna Müller-Esparza et al. Front Microbiol. .
No abstract available

Keywords: CRISPR; Cas proteins; Cascade; RNA interference; ribonucleoprotein.

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Figures

Figure 1
Figure 1
RNA targeting by Type I-F Cascade (A) Schematic representation of a Type I-F Cascade complex with bound DNA. The approximate location of the PAM near the large subunit (LSU, Csy1) is indicated. The reported target mRNA would bind at the opposite end of Cascade (near Cas7.6 and Cas6f). (B) The number of targets for each Pseudomonas aeruginosa strain UCBPP-PA14 spacer (5′-GGN-3′ followed by nine base-pair complementarity) in the genome (total targets) and transcriptome (mRNA targets) is indicated.
See this image and copyright information in PMC

Comment on

References

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