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Case Reports
. 2016 Dec 8:25:232.
doi: 10.11604/pamj.2016.25.232.10305. eCollection 2016.

Villoglandular papillary adenocarcinoma: case report

Affiliations
Case Reports

Villoglandular papillary adenocarcinoma: case report

Ghizlane Salek et al. Pan Afr Med J. .

Abstract

Villoglandular papillary adenocarcinoma (VPA) is a very rare subtype of adenocarcinoma of the uterine cervix, but a well-recognized variant of cervical adenocarcinoma with a favorable prognosis and generally occurring in women of child-bearing age. Herein, we report a case of VPA diagnosed and managed successfully with conservative measure. This management is particularly desirable in young women to preserve reproductive capability.

Keywords: Villoglandular; subtype of adenocarcinoma; young women.

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Conflict of interest statement

Author's declare no competing interest.

Figures

Figure 1
Figure 1
Hematein eosin x 5 villoglandular adenocarcinoma composed of papillary and glandular structures lined with cylindrical cells sometimes mucosecreting
Figure 2
Figure 2
HEx200 ADK villoglandular: glands lined with mucosecreting cylindrical cells (arrows) without invasive element
Figure 3
Figure 3
HEX400 details of papillary structures lined with columnar cells with moderate atypia with few mitotic figures (arrow)

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References

    1. Young RH, Scully RE. “Villoglandular papillary adenocarcinoma of the uterine cervix: a clinicopathologic analysis of 13 cases”. Cancer. 1989;63(9):1773–1779. - PubMed
    1. Jones MW, Silverberg SG, Kurman RJ. “Well-differentiated villoglandular adenocarcinoma of the uterine cervix: a clinicopathological study of 24 cases”. International Journal of Gynecological Pathology. 1993;12(1):1–7. - PubMed
    1. Liao SY, Manetta A. Benign and malignant pathology of the cervix, including screening. Curr Opin Obstet Gynecol. 1993;5:497–503. - PubMed
    1. Jones MW, Kaounelis S, Papadaki H, Bakker A, Swalsky PA, Woods J, et al. Well differentiated villoglandular adenocarcinoma of the uterine cervix: Oncogene/tumor suppressor gene alterations and human papillomavirus genotyping. Int J Gynecol Pathol. 2000;19:110–7. - PubMed
    1. Reed W, Abeler VM, Trope CG. Villous glandular adenocarcinoma of the uterine cervix. A subtype with favourable prognosis? Tidsskr Nor Laegeforen. 1993;113:2569–71. - PubMed

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