Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2016 Dec 8:25:232.
doi: 10.11604/pamj.2016.25.232.10305. eCollection 2016.

Villoglandular papillary adenocarcinoma: case report

Ghizlane Salek  1 , Issam Lalya  2 , Driss Moussaoui Rahali  1 , Mohamed Dehayni  1
Affiliations
Case Reports

Villoglandular papillary adenocarcinoma: case report

Ghizlane Salek et al. Pan Afr Med J. .

Abstract

Villoglandular papillary adenocarcinoma (VPA) is a very rare subtype of adenocarcinoma of the uterine cervix, but a well-recognized variant of cervical adenocarcinoma with a favorable prognosis and generally occurring in women of child-bearing age. Herein, we report a case of VPA diagnosed and managed successfully with conservative measure. This management is particularly desirable in young women to preserve reproductive capability.

Keywords: Villoglandular; subtype of adenocarcinoma; young women.

PubMed Disclaimer

Conflict of interest statement

Author's declare no competing interest.

Figures

Figure 1
Figure 1
Hematein eosin x 5 villoglandular adenocarcinoma composed of papillary and glandular structures lined with cylindrical cells sometimes mucosecreting
Figure 2
Figure 2
HEx200 ADK villoglandular: glands lined with mucosecreting cylindrical cells (arrows) without invasive element
Figure 3
Figure 3
HEX400 details of papillary structures lined with columnar cells with moderate atypia with few mitotic figures (arrow)
See this image and copyright information in PMC

References

    1. Young RH, Scully RE. “Villoglandular papillary adenocarcinoma of the uterine cervix: a clinicopathologic analysis of 13 cases”. Cancer. 1989;63(9):1773–1779. - PubMed
    1. Jones MW, Silverberg SG, Kurman RJ. “Well-differentiated villoglandular adenocarcinoma of the uterine cervix: a clinicopathological study of 24 cases”. International Journal of Gynecological Pathology. 1993;12(1):1–7. - PubMed
    1. Liao SY, Manetta A. Benign and malignant pathology of the cervix, including screening. Curr Opin Obstet Gynecol. 1993;5:497–503. - PubMed
    1. Jones MW, Kaounelis S, Papadaki H, Bakker A, Swalsky PA, Woods J, et al. Well differentiated villoglandular adenocarcinoma of the uterine cervix: Oncogene/tumor suppressor gene alterations and human papillomavirus genotyping. Int J Gynecol Pathol. 2000;19:110–7. - PubMed
    1. Reed W, Abeler VM, Trope CG. Villous glandular adenocarcinoma of the uterine cervix. A subtype with favourable prognosis? Tidsskr Nor Laegeforen. 1993;113:2569–71. - PubMed

Publication types